Pathology, Molecular Diagnostics, Research: Expertise

Urology Abstracts

  1. Shappell, S.B., Hughes, H., Smith, C.V., Moake, J., Mitchell, J.R.: Antioxidants may protect against ischemia-reflow injury by modulating reactive oxygen effects on cyclooxygenase/lipoxygenase products. Pharmacologist 29: 212a, 1987.
  2. Shappell, S.B., Taylor, A.A., Smith, C.W., Mitchell, J.R.: Non-antioxidant lipoxygenase inhibitors do not inhibit neutrophil function. Pharmacologist 30: 204a, 1988.
  3. Taylor, A.A., Shappell, S.B., Hughes, H., Mitchell, J.R.: Increased leukotriene-B4 measured by GC-MS in myocardial ischemia-reflow injury. Pharmacologist 30: 205a,1988.
  4. Gasic, A.C., Lenz, M.L., Kitt, T.M., Shappell, S.B., Mitchell, J.R., Taylor, A.A.: Myeloperoxidase activity: A reliable index of neutrophil accumulation in rabbit heart. FASEB J. 3: 742a, 1989.
  5. Shappell, S.B., Smith, C.W., Gasic, A.C., Taylor, A.A., Mitchell, J.R.: Effects of a specific LTB4 antagonist on human neutrophil function. FASEB J. 3: 595a, 1989.
  6. Kitt, T.M., Luderer, J.R., Shappell, S.B., Mitchell, J.R., Taylor, A.A., Smith, C.W.: The effect of U74006F, a novel aminosteroid on human neutrophil function. FASEB J. 3: 595a, 1989.
  7. Taylor, A., Gasic, A., Kitt, T., Shappell, S., Ruiz J., Lenz, M., Smith, C.W., Mitchell, J.R.: A specific leukotriene B4 antagonist protects against myocardial ischemia-reflow injury. Clin. Res. 37: 525a, 1989.
  8. Shappell, S.B., Toman, C., Anderson, D.C., Taylor, A.A., Smith, C.W.: Mac-1 (CD11b/CD18) participates in adherence-dependent neutrophil H2O2 production. Pharmacologist 31: 194a, 1989.
  9. Smith, C.W., Youker, K., Shappell, S.B., Rothlein, R., Entman, M.L.: CD 18-dependent adhesion of canine neutrophils to isolated adult canine myocytes. J. Leuk. Biol. 46: 311a, 1989.
  10. Shappell, S.B., Toman, C., Anderson, D.C., Taylor, A.A., Smith, C.W.: Adherence-dependent neutrophil hydrogen peroxide secretion is mediated by Mac-1 (CD11b/CD18). J. Leuk. Biol. 46: 306a, 1989.
  11. Shappell, S.B., McGuire, G.M., Hughes, H., Lane, C., Smith, C.W., Entman, M.L., Mitchell,J.R., Taylor, A.A. 5-lipoxygenase detection in isolated rabbit and canine cardiac myocytes. X International Symposium on Drugs Affecting Lipid Metabolism, 1989.
  12. Taylor, A.A., Gasic, A.C., Shappell, S.B., Kitt, T.M., Lenz, M.L., Smith, C.W., Mitchell, J.R.: Lipoxygenase products in myocardial ischemia-reflow injury: Protection by a leukotriene B4 antagonist and a nonantioxidant lipoxygenase inhibitor. X International Symposium on Drugs Affecting Lipid Metabolism, 1989.
  13. Shappell, S.B., Hughes, H., Youker, K., Entman, M.L., Wong, A., Mong, S., Taylor, A.A.: Detection of 5-lipoxygenase in isolated canine cardiac myocytes. FASEB J. 4: 624a, 1990.
  14. Mariscalco, M., Shappell, S., Anderson, D.C., Smith, C.W.: Role of CD18 in adherence-dependent hydrogen peroxide production by rabbit neutrophils. FASEB J. 4: 494a, 1990.
  15. Youker, K., Smith, C.W., Shappell, S.B., Michael, L.H., Rossen, R.D., Anderson, D.C., Entman, M.L.: Interleukin-6 contained in post-ischemic cardiac lymph induces CD18-dependent binding of activated neutrophils to isolated cardiac myocytes. Clin. Res. 38: 250a, 1990.
  16. Shappell, S.B., Taylor, A.A., Smith,C.W.: Mac-1 (CD11b/CD18) mediates adherence-dependent H2O2 production by neutrophils through protein kinase C activation. FASEB J 4: 2179a, 1990.
  17. Youker, K., Entman, M.L., Taylor, A.A., Shappell, S.B., Smith, C.W.: H2O2-induced adherence of neutrophils to canine cardiac myocytes is PAF-dependent and involves stimulation of CD11/CD18 adherence to ICAM-1. Circulation 82:III-275, 1990.
  18. Taylor, A.A., Shappell, S.B.: Reactive oxygen and lipoxygenase metabolites in myocardial ischemia reflow injury. ACS Symposium Series, 1990.
  19. Shappell, S.B., Taylor, A.A., Hughes, H., Smith, C.W.: Neutrophil (PMN) CD18-mediated adherence-dependent H2O2 production is accompanied by diacylglycerol (DAG) accumulation. J. Cell Biochem. (Suppl.) 15C: 225a, 1991.
  20. Entman, M.L. Youker, K., Toman, C.J., Beaudet, A.L., Lane, C.L., Dreyer, W.J., Shappell, S., Taylor, A.A., Rossen, R.D., Smith, C.W., Anderson, D.C.: Myocyte expression of ICAM-1: Critical factor in inflammatory injury. J. Cell Biochem. (Suppl.) 15C: 179a, 1991.
  21. Gentry, D.L., Hughes, H.,Shappell, S.B., Taylor, A.A.: Is PKC important in fMLP-stimulated arachidonic acid release in human neutrophils? FASEB J. 5: 1273a, 1991.
  22. Entman, M.L., Youker,K., Shoji, T., Taylor, A., Shappell,S., Smith, C.W.: Neutrophil-induced oxidative injury of cardiac myocytes is a compartmented system requiring CD11/CD18-ICAM-1 adherence. Clin. Res. 39: 159a, 1991.
  23. Taylor, A.A., Shappell, S.B., McGuire, G.M.: The 21-aminosteroid, U74006F, protects against rabbit myocardial reperfusion injury by a neutrophil-independent mechanism. FASEB J. 6(4): 1808, 1992.
  24. Gentry, D., Hughes, H., Shappell, S., Taylor, A.: Arachidonic acid release in PMNs occurs with R59022-ion induced CA2+ and diglycerol accumulation and is independent of PKC. FASEB J. 6(4): 665, 1992.
  25. Shappell, S.B., Smith, R.J., McGuire, G.M., Taylor, A.A.: Inhibition of neutrophil beta-2-integrin-mediated H2O2 production by lazaroids U75412 and U78517. FASEB J. 6(4): 2854, 1992.
  26. Hughes, B.J., Williams, S., Shappell, S., Robinson, M., Smith, C.W.: CD11b CD18 (Mac-1)-dependent neutrophil (PMN) functions: apparent role for affinity modulations. J. Leuk. Biol., 1992.
  27. Sarman, G., Shappell, S.B., Kaplan, S.L., Mason, E.O., Jr., Smith, C.W. Host response to systemic Escherichia Coli infection is impaired in intercellular adhesion molecule-1 (ICAM-1) deficient mutant mice. Ped. Res., 1994.
  28. Truong, L., Petrusevska, G., Yang, G., Gurpinar, T., Shappell, S., Lechago, J., Rouse, D., Suki, W. The kinetics of cell apoptosis and proliferation in chronic obstructive uropathy. J. Am. Soc. Nephrol. 6:888a, 1995.
  29. Shappell, S.B., Kukielka, G., Gurpinar, T., Smith, C.W., Suki, W., Truong, L. Upregulation of tubular cell ICAM-1 mediates inflammation in chronic obstructive uropathy. J. Am. Soc. Nephrol. 6:883a, 1995.
  30. Shappell, S.B., Thurman, L., Nagendra, A., Millman, E., Smith, C.W., Racusen, L., Truong, L. ICAM-1 dependent interaction of human neutrophils with cultured human proximal tubular epithelial cells. J. Am. Soc. Nephrol. 6:883a, 1995.
  31. Shappell, S., Brown, R.W., Truong, L.D. Atrophic renal tubules uniformly express Bcl-2 protein. An immunohistochemical study. Lab. Invest. 74:169a, 1996.
  32. Shappell, S.B., Gurpina, T., Smith, C.W., Truong, L.D. Chronic obstructive uropathy in the ICAM-1 deficient mouse. Lab. Invest. 74:169a, 1996.
  33. Truong, L., Yang, G., Nguyen, A., Shappell, S., Rouse, D., Jost, L., Gonzales, J., Suki, W. Improvement of renal lesions in chronic obstructive uropathy (COU) by enalapril is associated with a decrease in tubular cell apoptosis. J. Am. Soc. Nephrol. 7:1848a, 1996.
  34. Shappell, S.B., Gurpinar, T., Mendoza, L.H., Smith, C.W., Rouse, D., Suki, W.N., Truong, L.D. Lymphocyte infiltration is not required for progressive tubulointerstitial injury in chronic obstructive uropathy (COU). J. Am. Soc. Nephrol. 7:1745a, 1996.
  35. Truong, L., Petrusevska, G., Nguyen, K., Shappel, S., Lechago, J., Suki, W. Interstitial inflammatory infiltrates in experimental chronic obstructive uropathy (COU). Phenotypes and morphologic correlates. Mod. Pathol. 10:180a, 1997.
  36. Borowsky, A.D., Wingard, H.L., Brock, J.W., Shappell, S.B. Inflammatory fibrous pseudotumor of the spermatic cord/paratesticular region in a one year old boy; distinction from spindle cell rhabdomyosarcoma. Soc for Pediatric Pathology, 1997.
  37. Shappell, S.B., Snyder, S.B., Goral, S., Ynares,C., Fogo, A. Recurrent lupus nephritis in kidney transplants occurs at much higher frequency than reported. Lab. Invest. 78:149a, 1998.
  38. Nogueira, M., Cartwright, J., Horn, K., Doe, N., Eknoyan, G., Shappell, S., Barrios, R., Truong, L. Thin basement membrane disease (TBM) and heavy proteinuria: A report of seven cases. Lab. Invest. 78:148a, 1998.
  39. Wang, J-L., Cheng, H-F., Shappell, S., Harris, R.C. Cyclooxygenase-2 (COX-2) inhibition decreases proteinuria in the remnant kidney. J. Am. Soc. Nephrol. 9:625a, 1998.
  40. Kasper, S., Vaikunth, S., Thomas, T., Case, T., Thomas, J., Paul M., Masumori, N., Shappell, S., Matusik, R.J. Androgen independent progression of prostate cancer in LPBTag Transgenic Mice. 8th Annual Society for Basic Urologic Research, Prouts Neck Maine, 1998.
  41. Shappell, S.B., Boeglin, W.E., Olson, S.J., Brash, A.R. 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma. Lab. Invest. 79:107a, 1999.
  42. Thomas, T.Z., Shappell, S., Sohn, P.C., Kasper, S., Matusik, R.J., Moses, H.L., Serra, R.A. Expression of a truncated, kinase deficient TGFβ type II receptor in the mouse prostate. 81st Annual Meeting of The Endocrine Society, 1999.
  43. Matusik, R.J., Thomas, T., Masumori, N., Case, T., Paul, M., Thomas, J., Vaikunth, S., Lee, A., Price, R.R., Shappell, S., Kasper, S. Transgenic mouse models for prostate cancer. International Conference on Prostate Cancer Research, Iowa City, Iowa, 1999.
  44. Wang, J-L., Cheng, H-F., Shappell, S., Harris, R.C. Cyclooxygenase-2 (COX-2) inhibition decreases proteinuria in a hypertensive diabetic model. Am Soc of Nephrol, 1999.
  45. Brash, A.R., Boeglin, W.E., Schoenhard, J.A., Keeney, D.S., Carter, B., Shappell, S.B. 15-lipoxygenase-2 in human epithelial cells and its reduced expression in cancer. Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 6th International Conference, Boston, MA, 1999.
  46. Dutta, S.C., Shappell, S., Smith, J.A., Jr., Cookson, M.S. Radical cystectomy in high risk non-muscle invasive transitional carcinoma: Indications and outcomes. Southeastern Section of the American Urological Association, 1999.
  47. Dutta, S.C., Shappell, S., Smith, J.A., Jr., Cookson, M.S. Clinical understaging in patients with stage T1 transitional cell carcinoma of the bladder: Importance of muscularis propria in biopsy specimen. Southeastern Section of the American Urological Association, 1999.
  48. Grossklaus, D.J., Shappell, S.B., Gautam, S., Smith, J.A. Jr., Cookson, M.S. Correlation between percent free PSA and tumor volume in radical prostatectomy specimens. Southeastern Section of the American Urological Association, 1999
  49. Paueksakon, P., Revelo, M.P., Horn, R.G., Fogo, A., Shappell, S.B. Monoclonal gammopathy: Significance and possible causality in renal disease. United States and Canadian Academy of Pathology, 1999.
  50. Komhoff, M., Guan, Y., Shappell, S.B., Shappell, H.W., Shyr, Y., Koch, M., Jack, G.S., Breyer, M.D. Expression of cyclooxygenase-2 correlates with grade in transitional cell carcinoma. American Urological Association, 95th Annual Meeting, 2000.
  51. Thomas, T.Z., Shappell, S., Kasper, S., Serra, R.A., Moses, H.L., Matusik, R.J. Disruption of the TGFβ pathway in transgenic mice prevents castration-induced prostatic regression. American Urological Association, 95th Annual Meeting, 2000.
  52. Masumori, N., Vaikunth, S., Thomas, T.Z., Thomas, J., Tsukamoto, T., Case, T., Paul, M., Lee, H., Price, R.R., Chaurand, P., Caprioli, R., Kasper, S., Shappell, S., Matusik, R.J. Regrowth of prostate tumor after castration in probasin-large T antigen transgenic mice - longitudinal study with MRI. American Urological Association, 95th Annual Meeting, 2000.
  53. Masumori, N., Thomas, T.Z., Kasper, S., Chaurand, P., Caprioli, R., Tsukamoto, T., Shappell, S., Matusik, R.J. A probasin-large T antigen transgenic mouse line develops neuroendocrine and metastatic prostate cancer. American Urological Association, 95th Annual Meeting, 2000.
  54. Grossklaus, D.J., Shappell, S.B., Coffey, C.S., Cookson, M.S. Increasing biopsy number above sextant does not enhance prediction of tumor volume or pathologic stage. American Urological Association, 95th Annual Meeting, 2000.
  55. Grossklaus, DJ, Shappell, SB, Gautam, S, Smith, JA, Jr., Cooskon, MS. Correlation between percentfree PSA and tumor volume in radical prostatectomy specimens. American Urological Association, 95th Annual Meeting, 2000.
  56. Dutta, S.C., Shappell, S.B., Smith, J.A., Jr., Cookson, M.S. Clinical understaging in patients with stage T1 transitional cell carcinoma of the bladder: Importance of muscularis propria in biopsy specimen. American Urological Association, 95th Annual Meeting, 2000.
  57. Dutta, S.C., Shappell, S.B., Smith, J.A., Jr., Cookson, M.S. Radical cystectomy in high risk non-muscle invasive transitional cell carcinoma: Indications and outcomes. American Urological Association, 95th Annual Meeting, 2000.
  58. Chaurand, P., Masumori, N., Thomas, T.Z., Kasper, S., Dague, B.B., Shappell, S., Tsukamoto, T., Matusik, R.J., Caprioli, R.M. Following cancer progression by MALDI mass spectrometry. 48th ASMS Conference on Mass Spectrometry and Allied Topics, Long Beach, CA, June, 2000.
  59. Shappell, S.B., Manning, S., Boeglin, W.E., Jack, G.S., Guan, Y., Breyer, M.D., Wheeler, T.M., Brash, A.R. Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma. Advances in Prostaglandin and Leukotriene Research, 11th International Conference, Florence, Italy, June 2000.
  60. Jack, G.S., Brash, A.R., Olson, S.J., Manning, S., Coffey, C.S., Smith, J., Jr., Shappell, S.B. Reduced 15-lipoxygenase-2 in prostate carcinoma: correlation with tumor grade and high grade prostatic intraepithelial neoplasia. Advances in Prostaglandin and Leukotriene Research, 11th International Conference, Florence, Italy, June 2000.
  61. Shappell, S.B., Gupta, R., Manning, S., Boeglin, W.E., Cates, T., Jack, G.S., Whitehead, R., Price, J., Matusik, R.J., Brash, A.R., DuBois, R.N. 15S-HETE activates peroxisome proliferator activated receptor gamma and inhibits proliferation of prostate carcinoma PC3 cells. Advances in Prostaglandin and Leukotriene Research, 11th International Conference, Florence, Italy, June 2000.
  62. Grossklaus, DJ, Coffey, CS, Shappell, SB, Jack, GS, Cookson, MS. Prediction of tumor volume and pathologic stage in radical prostatectomy specimens is not enhanced by increasing the number of prostate needle biopsy cores. Presented at the Annual Meeting of the Southeastern Section of the AUA, New Orleans, LA, April 3, 2001.
  63. Grossklaus, DJ, Coffey, CS, Shappell, SB, Smith, JA, Jr., Cookson, MS. Percent free PSA correlates with prostate cancer pathology in radical prostatectomy specimens. Presented at the Annual Meeting of the Southeastern Section of the AUA, New Orleans, LA, April, 1, 2001.
  64. Grossklaus, DJ, Shappell, SB, Adams, MC, Brock, JW, III, Pope, JC, IV. Small intestine submucosa as a urethral coverage layer. Presented at the Annual Meeting of the Southeastern Section of the AUA, New Orleans, LA, March 31, 2001.
  65. Jack, G.S, Vader, V., Coffey, C.S., Cookson, M.S., Smith, J.A., Shappell, S.B. Pathological parameters in radical prostatectomies of clinical stage T1c versus T2 prostate carcinoma. The American Urological Association 96th Annual Meeting, June 2-7, 2001. Anaheim, California.
  66. Masumori N, Tu WH, Kasper S, Tsukamoto T, Shappell SB, Matusik RJ . Allograft model of androgen independent prostatic neuroendocrine carcinoma derived from LPB-TAG transgenic mouse line. The American Urological Association 96th Annual Meeting, June 2-7, 2001. Anaheim, California.
  67. Tu WH, Thomas TZ, Masumori N, Tsukamoto T, Kasper S, Roberts RL, Moses HL, Shappell SB, Matusik RJ. Role of TGF- B pathway in prostate carcinogenesis. The American Urological Association 96 th Annual Meeting, June 2-7, 2001. Anaheim, California.
  68. Revelo, MP, Smith, J.A., Jr., Shook, M.F., Cookson, M.S., Shappell, S.B. Incidence and location of prostate and urothelial carcinoma in prostates from cystoprostatectomies. Implications for possible apical sparing surgery. United States and Canadian Academy of Pathology, 2002 Annual Meeting.
  69. Roberts, R.L., Jack, G.S., Vader, V., Dave, D., Chang, S.S., Coffey, C.S., Smith, J.A., Jr., Cookson, M.S., Shappell, S.B. Comparison of transition zone and peripheral zone stage T1c prostate tumors. Pathologic distinctions in radical prostatectomies and biologic imnpliations. United States and Canadian Academy of Pathology, 2002 Annual Meeting.
  70. Gonzales, A.L., Roberts, R.L., Johnson, J.E., Olson, S.J., Shappell, S.B. 15-lipoxygenase-2 is expressed in type II pneumocytes and lung adenocarcinomas. United States and Canadian Academy of Pathology, 2002 Annual Meeting.
  71. Iyengar, S., Roberts, R.L., Manning, S., Xu, Y., Olson, S. J., Wheeler, T.M., Peehl, D.L., Shappell, S.B. Expression of peroxisome proliferator activated receptor regulated secretroy genes in benign and malignant prostate tissues. United States and Canadian Academy of Pathology, 2002 Annual Meeting.
  72. Vader, V., Roberts, R.L., Manning, S., Tu, W.H., Case, T., Shook, M.F., Olson, S.J., Matusik, R.J., Shappell, S.B. A peroxisome proliferator activated receptor gamma agonist inhibits metastases in a transgenic mouse model of prostate carcinoma. United States and Canadian Academy of Pathology, 2002 Annual Meeting
  73. Jack, G.S., Manning, S., Hannah, S.E., Brash, A.R., Vader, V., Case, T., Darrisaw, L., Olson, S.J., Smith, J.A.Jr, Matusik, R.J., Peehl, D.M., Shappell, S.B. Developmental and hormonal regulation of 15-lipoxygenase-2 expression in human prostate epithelium. Proc Am Assoc Cancer Res. 43: 231a, 2002.
  74. Vader, V., Roberts, R.L., Guan, Y.-F., Manning, S., Masumori, N., Olson, S.J., Shook, M.F., Coffey, C.S., Boeglin, W.E., Brash, A.R., Matusik, R.J., Shappell, S.B. A synthetic PPARγ agonist reduces tumor metastases and angiogenesis in a murine model of advanced androgen-insensitive prostate carcinoma. Proc Am Assoc Cancer Res. 43: 1083a, 2002.
  75. Shappell, S.B., Olson, S.J., Manning, S., Roberts, R.L., Masumori, N., Boeglin, W.E., Hannah, S.E., Vader, V., Shook, M.F., Thomas, T.Z., Brash, A.R., Matusik, R.J. Elevated expression of 12/15-lipoxygenase and COX-2 in a murine model of prostate carcinoma. Proc Am Assoc Cancer Res. 43: 390a, 2002.
  76. Revelo, M.P., Roberts, R.L., Olson, S.J., Davis, L., Breyer, M.D., Guan, Y.-F., Shappell, S.B. Prostaglandin E2 synthase expression in urinary bladder carcinoma: Correlation with cyclooxygenase-2 upregulation. Proc Am Assoc Cancer Res. 43: 399a, 2002.
  77. Iyengar, S., Manning, S., Shook, M.F., Olson, S.J., Wheeler, T.M., Gupta, R.A., Dubois, R.N., Shappell, S.B. Expression of peroxisome proliferator activated receptor γ (PPARγ) regulated genes in benign and malignant prostate tissue: correlation with 15-lipoxygenase-2 (15-LOX-2) expression. Proc Am Assoc Cancer Res. 43: 392a, 2002.
  78. Tu, W.H., Shyr, Y., Larsen, P., Levy, S., Kasper, S., Moses, H.L., Roberts, R.L., Shappell, S.B., Matusik, R.J. Loss of TGF-β signaling alters gene expression patterns and accelerates prostate tumorigenesis in transgenic mice. Proc Am Assoc Cancer Res. 43: 318a, 2002.
  79. Xu, X., Shappell, S.B., Song, S., Menter, D., Subbarayan, V., Lotan, R., Lippman, S.M. Differential expression of 15S-lipoxygenase-2 (15-LOX-2) in esophageal tissues and its modulation by nonsteroidal anti-inflammatory drugs (NSAIDs). Proc Am Assoc Cancer Res. 43: 310a, 2002.
  80. Grossklaus, D.J., Coffey, C.S., Shappell, S.B., Jack, G.S., Chang, S.S., Cookson, M.S. Percent of cancer in biopsy set predicts pathology following prostatectomy. American Urological Association 97 th Annual Meeting, 2002, Orlando, Fl.
  81. Cookson, M.S., Chang, S.S., Revelo, P., Shook, M.F., Smith, J.A., Shappell, S.B. Incidence and location of prostate and urothelial carcinoma in prostates from cystoprostatectomies: implications for apical sparing surgery. American Urological Association 97 th Annual Meeting, 2002, Orlando, Fl.
  82. Cookson, M.S., Chang, S.S., Girasole, C., Jack, G., Shappell, S.B., Smith, J.A. Pathologic parameters in radical prostatectomy specimens among men with high Gleason scores: cautious optimism in the PSA era. American Urological Association 97 th Annual Meeting, 2002, Orlando, Fl.
  83. Wilkerson, A., Olson, S.J., Brash, A.R., Page, R., Shappell, S.B.Increased 15-LOX-2 immunostaining in proliferative dermatoses. Possible role in regulation of keratinocyte proliferation and differentiation. United States and Canadian Academy of Pathology, 2003 Annual Meeting
  84. Dave, D.S., Revelo, M.P., Roberts, R., Jack, G.S., Smith, J.A., Jr., Chang, S.S.., Cookson, M.S., Shappell, S.B. Possible Determination of Transition Zone (TZ) vs. Peripheral Zone(PZ) Origin of Stage T1c Prostate Carcinoma (Pca) on Preoperative Biopsy by Assessment of Histological Features. United States and Canadian Academy of Pathology, 2003 Annual Meeting
  85. Shuford, M.D., Chang, S.S, Cookson, M.S., Shintani, A.K., Tsiatis, A., Smith, J.A., Jr., Shappell, S.B. Adverse prognostic significance of capsular incision after radical retropubic prostatectomy. J. Urol. 169 (4), Suppl.: 295a-296a, 2003. (American Urological Association 98 th Annual Meeting, 2003)
  86. Dave, D.S., Roberts, R.L., Olson, S.J., Hannah, S.E., Case, T., Shook, F., Shintani, A.K., Morrow, J.D., Matusik, R.J., Shappell, S.B. Chemopreventive effects of selective cyclooxygenase-2 (COX-2) inhibition of prostatic intraepithelial neoplasia in a transgenic mouse model of prostate carcinoma (Pca). J. Urol. 169 (4), Suppl.: 215a, 2003 (American Urological Association 98 th Annual Meeting, 2003)
  87. Masumori, N., Uchida, K., Matusik, R., Shappell, S., Tsukamoto, T. Early castration suppresses occurrence and development of neuroendocrine prostate carcinoma of the LPB-Tag 12T-10 transgenic mice. J Urol. 169 (4), Suppl.:87a, 2003 (American Urological Association 98 th Annual Meeting, 2003)
  88. Gonzalez, A.L., Roberts, R.L., Massion, P., Olson, S.J., Shyr, Y., Shappell, S.B. 15-Lipoxygenase-2 (15-LOX-2) expression in lung adenocarcinoma. Inverse correlation with tumor grade and proliferation. Proc Am Assoc Cancer Res, 2003.
  89. Roberts, R.L., Ishii, K., Hannah, E., Love, H., Hayward, S., Shappell, S.B. Androgens and peroxisome proliferator activated receptor (PPAR) γ agonists additively induce epithelial secretory differentiation in benign human prostate. Proc Am Assoc Cancer Res, 2003.
  90. Crooke, C.E., Takahashi, K., Faley, S.L., Jansen, D.E., Tomemori, T., Hannah, S.E., Shappell, S.B., Daniel, T.O., Takahashi, T. In vivo bioluminescence imaging of VEGF expression in transgenic mice. Soc Molecular Imaging, San Francisco, CA, Aug 2003.
  91. Revelo, M.P., Nelson, B., Smith, J.A. , Jr., Shappell, S.B., Cookson, M.S., Chang, S. Prognostic factors in penile carcinoma. United States and Canadian Academy of Pathology, 2004 Annual Meeting
  92. Nelson, B.A., Chang, S.S., Duong, D., Farnham, S.B., Shappell, S.B., Wells, N, Smith, J.A., Jr., Cookson, M.A. Obesity is positively correlated with PSA recurrence and time to PSA recurrence in patients undergoing radical prostatectomy. J. Urol. 171 (4), Suppl.:120a, 2004 (American Urological Association 99 th Annual Meeting, 2004)
  93. Farnham, S.B., Revelo, M.P., Harrison, P.L., West, H.E., Cookson, M.S., Chang, S.S., Smith, J.A., Jr., Shappell, S.B. Is length of positive surgical margin an independent predictor of biochemical progression after prostatectomy? Results of a multivariate analysis. J. Urol. 171 (4), Suppl.:224a, 2004 (American Urological Association 99 th Annual Meeting, 2004)
  94. Nelson, B.A., Shappell, S.B., Farnham, S.B., Chang, S.S., Smith, J.A., Jr., Cookson, M.S. Tumor volume is positively correlated with pathologic stage and PSA recurrence in patients undergoing radical prostatectomy. J. Urol. 171 (4), Suppl.:224a, 2004 (American Urological Association 99 th Annual Meeting, 2004)
  95. Nelson, B.A., Cookson, M.S., Smith, J.A., Jr., Shappell, S.B., Chang, S.S. Squamous cell carcinoma of the penis: A contemporary review of lymph node disease. J. Urol. 173 (4), Suppl.:198a, 2005 (American Urological Association 100 th Annual Meeting, 2005)
  96. Shappell, S.B., Lewis, P.A., Roberts, R.L., Brittin, G.M., Roberts, K., Rigler, W., Schildcrout, J., Putzi, M.J., Oppenheimer, J.R. Coordinated use of urine cytology and UroVysion FISH in diagnosing recurrent and new urothelial carcinoma. J. Urol. 173 (4), Suppl.:231a, 2005 (American Urological Association 100 th Annual Meeting, 2005)
  97. Girasole, C.R., Cookson, M.S., Putzi, M.J., Chang, S.S., Smith, J.A., Wells, N., Shappell, S.B., Oppenheimer, J.R. Significance of ASAP and HGPIN on prostate biopsy: implications for cancer detection and biopsy strategy. J. Urol. 173 (4), Suppl.:404a, 2005 (American Urological Association 100 th Annual Meeting, 2005)
  98. Girasole, C.R., Cookson, M.S., Putzi, M.J., Chang, S.S., Smith, J.A., Wells, N., Oppenheimer, J.R., Shappell, S.B. Incidence and significance of HGPIN on prostate biopsy: Results of a large, community-based pathology referal center. J. Urol. 173 (4), Suppl.:397a, 2005 (American Urological Association 100 th Annual Meeting, 2005)
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